Product Data Sheet
Baricitinib 4-aminobenzoic acid TFA
Catalog No. A33406
Baricitinib 4-aminobenzoic acid TFA is a Target Protein Ligand-Linker Conjugate that features a ligand for JAK2 alongside a PROTAC linker designed to facilitate the recruitment of E3 ligases. This compound serves as a critical component in the synthesis of the PROTAC JAK2 degrader SJ1008030, enabling targeted degradation of the JAK2 protein. It is particularly relevant for research focused on JAK2-related pathways and potential therapeutic strategies against related diseases.
Chemical Information
| Catalog Num | A33406 |
|---|---|
| M. Wt | 620.56 |
| Formula | C25H23F3N8O6S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2789680-32-4 |
| Synonyms | |
| SMILES | N#CCC1(CN(S(=O)(CC)=O)C1)N(N=C2)C=C2C3=NC(NC(C=C4)=CC=C4C(O)=O)=NC5=C3C=CN5.OC(C(F)(F)F)=O |
Biological Activity
| Description | Baricitinib 4-aminobenzoic acid TFA is a Target Protein Ligand-Linker Conjugate that features a ligand for JAK2 alongside a PROTAC linker designed to facilitate the recruitment of E3 ligases. This compound serves as a critical component in the synthesis of the PROTAC JAK2 degrader SJ1008030, enabling targeted degradation of the JAK2 protein. It is particularly relevant for research focused on JAK2-related pathways and potential therapeutic strategies against related diseases. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
