Product Data Sheet
TYK2-IN-11
Catalog No. A33423
TYK2-IN-11 is a selective inhibitor of Tyk-2, exhibiting IC50 values of 0.016 nM for TYK2-JH2 and 0.31 nM for JAK1-JH2. This compound is valuable for investigating the role of Tyk-2 in inflammatory and autoimmune diseases. Its high potency and selectivity make it a critical tool in the research of signaling pathways associated with these conditions.
Chemical Information
| Catalog Num | A33423 |
|---|---|
| M. Wt | 383.42 |
| Formula | C18H17N5O3S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2757009-40-6 |
| Synonyms | |
| SMILES | O=C(C)NC1=CC(NC2=CC=CC(S(=O)(C)=O)=N2)=C(C3=NC=CC=C3)C=N1 |
Biological Activity
| Description | TYK2-IN-11 is a selective inhibitor of Tyk-2, exhibiting IC50 values of 0.016 nM for TYK2-JH2 and 0.31 nM for JAK1-JH2. This compound is valuable for investigating the role of Tyk-2 in inflammatory and autoimmune diseases. Its high potency and selectivity make it a critical tool in the research of signaling pathways associated with these conditions. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
