Product Data Sheet

TCB-32

Catalog No. A33461

main product photo
TCB-32 is a potent FGFR1 agonist with an EC50 of 0.88 μM, effectively activating the FGFR1 signaling pathway to enhance cell proliferation, notably through the ERK 1/2 cascade. This compound exhibits excellent thermal stability and can serve as a substitute for bFGF in serum-free cell culture environments. TCB-32 is applicable in research related to tissue repair and wound healing, making it suitable for studies investigating conditions such as psoriasis and eczema.
Chemical Information
Catalog NumA33461
M. Wt708.78
FormulaC32H40N18O2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.352513-86-1
Synonyms
SMILESC/C(C1=CC(NC(C2=CC(C(NC3=CC(/C(C)=N/NC(N)=N)=CC(/C(C)=N/NC(N)=N)=C3)=O)=CC=C2)=O)=CC(/C(C)=N/NC(N)=N)=C1)=N\NC(N)=N
Biological Activity
DescriptionTCB-32 is a potent FGFR1 agonist with an EC50 of 0.88 μM, effectively activating the FGFR1 signaling pathway to enhance cell proliferation, notably through the ERK 1/2 cascade. This compound exhibits excellent thermal stability and can serve as a substitute for bFGF in serum-free cell culture environments. TCB-32 is applicable in research related to tissue repair and wound healing, making it suitable for studies investigating conditions such as psoriasis and eczema.
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SHIPPING AND STORAGE
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