Product Data Sheet
Pazopanib-13C,d3
Catalog No. A33534
Pazopanib-13C,d3 is a stable isotope-labeled form of Pazopanib, a potent multi-target inhibitor primarily affecting VEGFR1, VEGFR2, VEGFR3, PDGFRβ, c-Kit, FGFR1, and c-Fms with respective IC50 values of 10, 30, 47, 84, 74, 140, and 146 nM. This isotope-labeled compound is valuable in pharmacokinetic studies and metabolic research applications, facilitating the exploration of drug metabolism and distribution in biological systems. Ideal for use in quantitative analysis and imaging studies, Pazopanib-13C,d3 enhances the understanding of tumor angiogenesis and targeted cancer therapies.
Chemical Information
| Catalog Num | A33534 |
|---|---|
| M. Wt | 441.53 |
| Formula | C2013CH20D3N7O2S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1261734-88-6 |
| Synonyms | GW786034-13C,d3 |
| SMILES | CC1=C2C(C=C(C=C2)N(C3=NC(NC4=CC(S(N)(=O)=O)=C(C=C4)C)=NC=C3)[13C]([2H])([2H])[2H])=NN1C |
Biological Activity
| Description | Pazopanib-13C,d3 is a stable isotope-labeled form of Pazopanib, a potent multi-target inhibitor primarily affecting VEGFR1, VEGFR2, VEGFR3, PDGFRβ, c-Kit, FGFR1, and c-Fms with respective IC50 values of 10, 30, 47, 84, 74, 140, and 146 nM. This isotope-labeled compound is valuable in pharmacokinetic studies and metabolic research applications, facilitating the exploration of drug metabolism and distribution in biological systems. Ideal for use in quantitative analysis and imaging studies, Pazopanib-13C,d3 enhances the understanding of tumor angiogenesis and targeted cancer therapies. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
