Product Data Sheet

BCR-ABL kinase-IN-3

Catalog No. A33654

main product photo
BCR-ABL kinase-IN-3 is a potent inhibitor of the BCR-ABL fusion protein, a critical driver in the pathology of acute myeloid leukemia (AML). This compound exhibits significant biological activity in inhibiting the kinase activity, making it a valuable tool for research into therapeutic strategies targeting BCR-ABL-related malignancies. Its application spans the investigation of molecular mechanisms underlying leukemia and the development of innovative treatments for improved patient outcomes.
Chemical Information
Catalog NumA33654
M. Wt611.67
FormulaC35H30FN9O
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2699634-21-2
Synonyms
SMILESCN(N=C1)C=C1NC2=CC=CN3C2=NC=C3C#CC4=C(C)C=C(F)C(C(NC5=CC(N6C=C(C)N=C6)=CC(C(C#N)(C)C)=C5)=O)=C4
Biological Activity
DescriptionBCR-ABL kinase-IN-3 is a potent inhibitor of the BCR-ABL fusion protein, a critical driver in the pathology of acute myeloid leukemia (AML). This compound exhibits significant biological activity in inhibiting the kinase activity, making it a valuable tool for research into therapeutic strategies targeting BCR-ABL-related malignancies. Its application spans the investigation of molecular mechanisms underlying leukemia and the development of innovative treatments for improved patient outcomes.
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