Product Data Sheet
HP1328
Catalog No. A33696
HP1328 is a potent inhibitor of the FLT3 receptor tyrosine kinase specifically targeting the FLT3/ITD mutation. This benzoimidazole scaffold-based compound demonstrates significant efficacy in reducing leukemia burden and prolonging survival in murine models of FLT3/ITD leukemia. HP1328 is valuable for research focused on targeted therapies for acute myeloid leukemia and advancing understanding of FLT3-related pathophysiology.
Chemical Information
| Catalog Num | A33696 |
|---|---|
| M. Wt | 389.45 |
| Formula | C23H23N3O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2245074-20-6 |
| Synonyms | |
| SMILES | OCCOC1=CC=C(CNC2=CC(N=CN3C4=CC=CC=C4)=C3C=C2)C=C1OC |
Biological Activity
| Description | HP1328 is a potent inhibitor of the FLT3 receptor tyrosine kinase specifically targeting the FLT3/ITD mutation. This benzoimidazole scaffold-based compound demonstrates significant efficacy in reducing leukemia burden and prolonging survival in murine models of FLT3/ITD leukemia. HP1328 is valuable for research focused on targeted therapies for acute myeloid leukemia and advancing understanding of FLT3-related pathophysiology. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
