Product Data Sheet
FLT3-IN-32 TFA
Catalog No. A33698
FLT3-IN-32 TFA is a selective inhibitor of FLT3, targeting both FLT3-ITD and FLT3-D835Y with IC50 values of 2.40 nM and 3.83 nM, respectively. This compound effectively inhibits the proliferation and survival of human MV4-11 cells, demonstrating an IC50 of 0.07 nM. FLT3-IN-32 TFA is valuable for research focused on acute myeloid leukemia (AML), providing insights into targeted therapeutic strategies.
Chemical Information
| Catalog Num | A33698 |
|---|---|
| M. Wt | 629.58 |
| Formula | C30H30F3N5O7 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 3047195-49-0 |
| Synonyms | |
| SMILES | O=C(NC1=CC2=C(OC(C(C3=CC4=C(CN(C)C)C(O)=CC=C4N3)=O)=C2)C=C1)NC5=NOC(C(C)(C)C)=C5.O=C(O)C(F)(F)F |
Biological Activity
| Description | FLT3-IN-32 TFA is a selective inhibitor of FLT3, targeting both FLT3-ITD and FLT3-D835Y with IC50 values of 2.40 nM and 3.83 nM, respectively. This compound effectively inhibits the proliferation and survival of human MV4-11 cells, demonstrating an IC50 of 0.07 nM. FLT3-IN-32 TFA is valuable for research focused on acute myeloid leukemia (AML), providing insights into targeted therapeutic strategies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
