Product Data Sheet
FLT3/ITD-IN-5
Catalog No. A33704
FLT3/ITD-IN-5 is a potent inhibitor of FLT3 and FLT3-ITD, exhibiting IC50 values of 0.088 nM and 0.348 nM, respectively. This compound is designed for use in cancer research, providing valuable insights into therapies targeting FLT3 mutations commonly found in acute myeloid leukemia (AML). Its high selectivity makes it an essential tool for studying FLT3 signaling pathways and developing targeted treatments.
Chemical Information
| Catalog Num | A33704 |
|---|---|
| M. Wt | 431.49 |
| Formula | C23H25N7O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 3023632-62-1 |
| Synonyms | |
| SMILES | CCC1=C(C(C2=O)=NN1C)/C=C/C3=NNC4=CC=C(C(C=N5)=C(OCCN2C)N5C)C=C34 |
Biological Activity
| Description | FLT3/ITD-IN-5 is a potent inhibitor of FLT3 and FLT3-ITD, exhibiting IC50 values of 0.088 nM and 0.348 nM, respectively. This compound is designed for use in cancer research, providing valuable insights into therapies targeting FLT3 mutations commonly found in acute myeloid leukemia (AML). Its high selectivity makes it an essential tool for studying FLT3 signaling pathways and developing targeted treatments. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
