Product Data Sheet

HP1142

Catalog No. A33724

main product photo
HP1142 is a selective inhibitor of the FLT3 receptor tyrosine kinase, specifically targeting the FLT3/ITD mutation. This compound, derived from a benzoimidazole scaffold, demonstrates significant efficacy in inhibiting FLT3 signaling pathways. HP1142 is primarily utilized in research focused on FLT3/ITD mutated leukemia, providing valuable insights into therapeutic strategies for this malignancy.
Chemical Information
Catalog NumA33724
M. Wt359.42
FormulaC22H21N3O2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.381173-58-6
Synonyms
SMILESCOC(C(OC)=C1)=CC=C1CNC2=CC3=C(C=C2)N(C4=CC=CC=C4)C=N3
Biological Activity
DescriptionHP1142 is a selective inhibitor of the FLT3 receptor tyrosine kinase, specifically targeting the FLT3/ITD mutation. This compound, derived from a benzoimidazole scaffold, demonstrates significant efficacy in inhibiting FLT3 signaling pathways. HP1142 is primarily utilized in research focused on FLT3/ITD mutated leukemia, providing valuable insights into therapeutic strategies for this malignancy.
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SHIPPING AND STORAGE
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