Product Data Sheet
Proinsulin C-peptide (human)
Catalog No. A33747
Proinsulin C-peptide (human) is a 31-amino acid peptide that facilitates the proper folding of proinsulin by connecting its A and B chains. This peptide has been shown to inhibit high glucose-induced upregulation of PDGF-β receptor protein expression and the phosphorylation of p42/p44 MAP kinase. Additionally, Proinsulin C-peptide enhances the deformability of erythrocytes in type 1 diabetes and suppresses the proliferation of rat aortic smooth muscle cells under hyperglycemic conditions, with potential implications for vascular complications in diabetes research.
Chemical Information
| Catalog Num | A33747 |
|---|---|
| M. Wt | 3020.26 |
| Formula | C129H211N35O48 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 33017-11-7 |
| Synonyms | |
| SMILES | C([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC(CNC(=O)[C@H]1N(C(CNC(CNC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CCC(O)=O)N)=O)C)=O)CCC(O)=O)=O)CC(O)=O)=O)CC(C)C)=O)CCC(N)=O)=O)C(C)C)=O)=O)CCC(N)=O)=O)[C@H](C)C)=O)CCC(O)=O)=O)CC(C)C)=O)=O)=O)=O)CCC1)=O)C)=O)=O)CO)=O)CC(C)C)=O)CCC(N)=O)(=O)N2[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@@H](CCC(N)=O)C(O)=O)=O)CC(C)C)=O)CO)=O)=O)CCC(O)=O)=O)CC(C)C)=O)C)=O)CC(C)C)=O)CCC2 |
Biological Activity
| Description | Proinsulin C-peptide (human) is a 31-amino acid peptide that facilitates the proper folding of proinsulin by connecting its A and B chains. This peptide has been shown to inhibit high glucose-induced upregulation of PDGF-β receptor protein expression and the phosphorylation of p42/p44 MAP kinase. Additionally, Proinsulin C-peptide enhances the deformability of erythrocytes in type 1 diabetes and suppresses the proliferation of rat aortic smooth muscle cells under hyperglycemic conditions, with potential implications for vascular complications in diabetes research. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
