Product Data Sheet

(R)-(-)-α-Methylhistamine dihydrochloride

Catalog No. A33830

main product photo
(R)-(-)-α-Methylhistamine dihydrochloride is a potent and selective agonist for the H3 histamine receptor, demonstrating a Kd of 50.3 nM. This compound has been shown to enhance memory retention and reduce memory impairment in preclinical models, making it valuable for research focused on cognitive function and neurological disorders. Its ability to penetrate the blood-brain barrier further supports its potential in brain-related studies.
Chemical Information
Catalog NumA33830
M. Wt198.09
FormulaC6H13Cl2N3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.75614-89-0
Synonyms
SMILES[H]Cl.[H]Cl.C[C@@H](N)CC1=CN=CN1
Biological Activity
Description(R)-(-)-α-Methylhistamine dihydrochloride is a potent and selective agonist for the H3 histamine receptor, demonstrating a Kd of 50.3 nM. This compound has been shown to enhance memory retention and reduce memory impairment in preclinical models, making it valuable for research focused on cognitive function and neurological disorders. Its ability to penetrate the blood-brain barrier further supports its potential in brain-related studies.
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