Product Data Sheet

Tiotidine

Catalog No. A33835

main product photo
Tiotidine is a selective antagonist of the histamine H2 receptor, exhibiting a pA2 value of 7.3-7.8 in the guinea pig right atrium. This compound demonstrates low affinity for H1 and H3 receptors, allowing for targeted modulation of H2 receptor activity. Tiotidine is primarily used in research applications related to gastric acid secretion and histamine-related signaling pathways.
Chemical Information
Catalog NumA33835
M. Wt312.42
FormulaC10H16N8S2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.69014-14-8
SynonymsICI 125211
SMILESCN/C(NC#N)=N\CCSCC1=CSC(NC(N)=N)=N1
Biological Activity
DescriptionTiotidine is a selective antagonist of the histamine H2 receptor, exhibiting a pA2 value of 7.3-7.8 in the guinea pig right atrium. This compound demonstrates low affinity for H1 and H3 receptors, allowing for targeted modulation of H2 receptor activity. Tiotidine is primarily used in research applications related to gastric acid secretion and histamine-related signaling pathways.
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