Product Data Sheet

Imetit dihydrobromide

Catalog No. A33844

main product photo
Imetit dihydrobromide is a potent and selective agonist of the histamine H3 and H4 receptors, exhibiting binding affinities with Ki values of 0.3 nM and 2.7 nM, respectively. This compound effectively mimics histamine, inducing morphological changes in eosinophils, with an EC50 value of 25 nM. Imetit dihydrobromide is valuable for researching mechanisms related to allergic responses and inflammation modulation.
Chemical Information
Catalog NumA33844
M. Wt332.06
FormulaC6H12Br2N4S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.32385-58-3
SynonymsVUF 8325 dihydrobromide; SKF 91105 dihydrobromide
SMILESNC(SCCC1=CN=CN1)=N.Br.Br
Biological Activity
DescriptionImetit dihydrobromide is a potent and selective agonist of the histamine H3 and H4 receptors, exhibiting binding affinities with Ki values of 0.3 nM and 2.7 nM, respectively. This compound effectively mimics histamine, inducing morphological changes in eosinophils, with an EC50 value of 25 nM. Imetit dihydrobromide is valuable for researching mechanisms related to allergic responses and inflammation modulation.
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