Product Data Sheet

Oxomemazine

Catalog No. A33903

main product photo
Oxomemazine is a phenothiazine-derived antagonist targeting the histamine H1 receptor. It exhibits notable antihistamine and anticholinergic properties, making it useful in research related to cough treatments. Additionally, Oxomemazine demonstrates a selective blockade of the muscarinic M1 receptor with a significant affinity difference compared to the M2 receptor. Studies have shown its protective effects against anaphylactic microshock in guinea pigs, highlighting its potential for further pharmacological investigation.
Chemical Information
Catalog NumA33903
M. Wt330.44
FormulaC18H22N2O2S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.3689-50-7
Synonyms
SMILESCC(CN1C2=C(C=CC=C2)S(C3=CC=CC=C13)(=O)=O)CN(C)C
Biological Activity
DescriptionOxomemazine is a phenothiazine-derived antagonist targeting the histamine H1 receptor. It exhibits notable antihistamine and anticholinergic properties, making it useful in research related to cough treatments. Additionally, Oxomemazine demonstrates a selective blockade of the muscarinic M1 receptor with a significant affinity difference compared to the M2 receptor. Studies have shown its protective effects against anaphylactic microshock in guinea pigs, highlighting its potential for further pharmacological investigation.
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