Product Data Sheet
Sch-40338
Catalog No. A33966
Sch-40338 is a dual antagonist targeting platelet-activating factor (PAF) and histamine, exhibiting an IC50 of 0.59 μM in PAF-induced platelet aggregation and a Ki of 5.4 μM for histamine H₁ receptor binding. This compound is valuable for investigating the mechanisms underlying allergic diseases, offering insights into the modulation of inflammatory responses and platelet activation pathways. Sch-40338 serves as a useful tool for researchers exploring therapeutic strategies in allergen-mediated conditions.
Chemical Information
| Catalog Num | A33966 |
|---|---|
| M. Wt | 355.86 |
| Formula | C20H22ClN3O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 117796-62-0 |
| Synonyms | |
| SMILES | CC(N1CCN(CC1)C2C3=CC=C(C=C3CCC4=CC=CN=C24)Cl)=O |
Biological Activity
| Description | Sch-40338 is a dual antagonist targeting platelet-activating factor (PAF) and histamine, exhibiting an IC50 of 0.59 μM in PAF-induced platelet aggregation and a Ki of 5.4 μM for histamine H₁ receptor binding. This compound is valuable for investigating the mechanisms underlying allergic diseases, offering insights into the modulation of inflammatory responses and platelet activation pathways. Sch-40338 serves as a useful tool for researchers exploring therapeutic strategies in allergen-mediated conditions. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
