Product Data Sheet
Immethridine dihydrobromide
Catalog No. A33980
Immethridine dihydrobromide is a selective agonist of the histamine H3 receptor (H3R) and demonstrates 300-fold selectivity for H3R over the H4 receptor, with no binding affinity for H1 or H2 receptors. This compound is valuable for research applications related to experimental autoimmune encephalomyelitis (EAE), providing insights into the role of H3R in neuroinflammatory conditions. Its specific targeting of H3R makes it a significant tool for investigating therapeutic approaches in neurological disorders.
Chemical Information
| Catalog Num | A33980 |
|---|---|
| M. Wt | 321.01 |
| Formula | C9H11Br2N3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 699020-93-4 |
| Synonyms | |
| SMILES | [H]Br.[H]Br.C1(CC2=CN=CN2)=CC=NC=C1 |
Biological Activity
| Description | Immethridine dihydrobromide is a selective agonist of the histamine H3 receptor (H3R) and demonstrates 300-fold selectivity for H3R over the H4 receptor, with no binding affinity for H1 or H2 receptors. This compound is valuable for research applications related to experimental autoimmune encephalomyelitis (EAE), providing insights into the role of H3R in neuroinflammatory conditions. Its specific targeting of H3R makes it a significant tool for investigating therapeutic approaches in neurological disorders. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
