NNC 38-1049
Catalog No. A33994

NNC 38-1049 is a potent and competitive antagonist of the histamine H3 receptor, demonstrating oral bioactivity. It effectively increases extracellular histamine levels in the paraventricular nucleus, suggesting potential implications in modulating neurotransmitter release. Research applications include the investigation of its effects on food intake and body weight regulation, making it a valuable tool for obesity studies.
Chemical Information
| Catalog Num | A33994 |
|---|---|
| M. Wt | 348.87 |
| Formula | C19H25ClN2O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 757183-18-9 |
| Synonyms | |
| SMILES | O=C(C1=CC=C(Cl)C=C1)CCC(N2CCN(C3CCCC3)CC2)=O |
Biological Activity
| Description | NNC 38-1049 is a potent and competitive antagonist of the histamine H3 receptor, demonstrating oral bioactivity. It effectively increases extracellular histamine levels in the paraventricular nucleus, suggesting potential implications in modulating neurotransmitter release. Research applications include the investigation of its effects on food intake and body weight regulation, making it a valuable tool for obesity studies. |
|---|
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


