Product Data Sheet
Toladryl
Catalog No. A34004
Toladryl is an antihistamine drug with the ability to penetrate the blood-brain barrier, demonstrating both oral bioavailability and antihistaminic as well as anticholinergic properties. Its anticholinergic activity is approximately one-tenth that of diphenhydramine, while its protective efficacy against lethal doses of histamine in guinea pigs is 2-4 times greater. Toladryl exhibits milder and fewer side effects compared to diphenhydramine; however, higher doses may lead to central nervous system symptoms, including insomnia and agitation. This compound is valuable for research in the field of allergic diseases.
Chemical Information
| Catalog Num | A34004 |
|---|---|
| M. Wt | 269.38 |
| Formula | C18H23NO |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 19804-27-4 |
| Synonyms | 4-Methyldiphenhydramine |
| SMILES | CN(C)CCOC(C1=CC=CC=C1)C2=CC=C(C)C=C2 |
Biological Activity
| Description | Toladryl is an antihistamine drug with the ability to penetrate the blood-brain barrier, demonstrating both oral bioavailability and antihistaminic as well as anticholinergic properties. Its anticholinergic activity is approximately one-tenth that of diphenhydramine, while its protective efficacy against lethal doses of histamine in guinea pigs is 2-4 times greater. Toladryl exhibits milder and fewer side effects compared to diphenhydramine; however, higher doses may lead to central nervous system symptoms, including insomnia and agitation. This compound is valuable for research in the field of allergic diseases. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
