Product Data Sheet
DA 4643 dihydrochloride
Catalog No. A34027
DA 4643 dihydrochloride is an H2 receptor antagonist known for its unique properties in lipid peroxidation inhibition. This compound, with the chemical structure 2-guanidino-4 (3-methylaminomethyleneiminophenyl) thiazole dihydrochloride, exhibits antioxidant activity that contributes to its ability to suppress both enzymatic and non-enzymatic lipid peroxidation reactions. Unlike other H2 receptor antagonists, DA 4643 shows a weaker interaction with cytochrome P-450, further highlighting its distinct pharmacological profile. This makes DA 4643 dihydrochloride a valuable tool for studying H2 receptor-mediated pathways and oxidative stress in various biological contexts.
Chemical Information
| Catalog Num | A34027 |
|---|---|
| M. Wt | 347.27 |
| Formula | C12H16Cl2N6S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 95833-19-5 |
| Synonyms | |
| SMILES | C/N=C/NC1=CC=CC(C2=CSC(NC(N)=N)=N2)=C1.Cl.Cl |
Biological Activity
| Description | DA 4643 dihydrochloride is an H2 receptor antagonist known for its unique properties in lipid peroxidation inhibition. This compound, with the chemical structure 2-guanidino-4 (3-methylaminomethyleneiminophenyl) thiazole dihydrochloride, exhibits antioxidant activity that contributes to its ability to suppress both enzymatic and non-enzymatic lipid peroxidation reactions. Unlike other H2 receptor antagonists, DA 4643 shows a weaker interaction with cytochrome P-450, further highlighting its distinct pharmacological profile. This makes DA 4643 dihydrochloride a valuable tool for studying H2 receptor-mediated pathways and oxidative stress in various biological contexts. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
