Product Data Sheet
JNJ-28583867
Catalog No. A34047
JNJ-28583867 is a selective histamine H3 receptor antagonist with a Ki of 10.6 nM and an inhibitor of the serotonin transporter (SERT) with a Ki of 3.7 nM. This compound shows promise in modulating neurotransmitter systems and can be utilized in research focusing on depression and related neuropsychiatric disorders. Its unique mechanism makes it a valuable tool for studying the interplay between histaminergic and serotonergic pathways.
Chemical Information
| Catalog Num | A34047 |
|---|---|
| M. Wt | 412.59 |
| Formula | C24H32N2O2S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 892407-39-5 |
| Synonyms | |
| SMILES | CSC1=CC=C([C@@H]2CN(C)CC3=C2C=CC(OCCCN4CCOCC4)=C3)C=C1 |
Biological Activity
| Description | JNJ-28583867 is a selective histamine H3 receptor antagonist with a Ki of 10.6 nM and an inhibitor of the serotonin transporter (SERT) with a Ki of 3.7 nM. This compound shows promise in modulating neurotransmitter systems and can be utilized in research focusing on depression and related neuropsychiatric disorders. Its unique mechanism makes it a valuable tool for studying the interplay between histaminergic and serotonergic pathways. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
