IT 066 hydrochloride
Catalog No. A34064

IT 066 hydrochloride is a potent Histamine H2 receptor antagonist. This compound demonstrates antioxidant activity and has been shown to protect against acute gastric mucosal injury due to ischemia-reperfusion in rat models. Additionally, IT 066 hydrochloride effectively inhibits secretagogue-induced gastric acid secretion and exhibits a long-lasting anti-lesion effect on experimental gastric and duodenal lesions. It is a valuable tool for researching gastrointestinal diseases and understanding the mechanisms of gastric protection and acid regulation.
Chemical Information
| Catalog Num | A34064 |
|---|---|
| M. Wt | 392.88 |
| Formula | C19H25ClN4O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 126463-66-9 |
| Synonyms | |
| SMILES | O=C1C(C(N)=C1NC/C=C\COC2=NC=CC(CN3CCCCC3)=C2)=O.Cl |
Biological Activity
| Description | IT 066 hydrochloride is a potent Histamine H2 receptor antagonist. This compound demonstrates antioxidant activity and has been shown to protect against acute gastric mucosal injury due to ischemia-reperfusion in rat models. Additionally, IT 066 hydrochloride effectively inhibits secretagogue-induced gastric acid secretion and exhibits a long-lasting anti-lesion effect on experimental gastric and duodenal lesions. It is a valuable tool for researching gastrointestinal diseases and understanding the mechanisms of gastric protection and acid regulation. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


