Product Data Sheet

Loratadine n-oxide

Catalog No. A34094

main product photo
Loratadine n-oxide is a metabolite of the antihistamine Loratadine, acting as a competitive antagonist of peripheral histamine H1 receptors. This compound exhibits antihistaminic activity, making it useful in research focused on allergic responses and related pathways. Its role in understanding the pharmacokinetics and pharmacodynamics of antihistamines provides valuable insights for studies on allergy treatment and management.
Chemical Information
Catalog NumA34094
M. Wt398.88
FormulaC22H23ClN2O3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.165739-62-8
Synonyms
SMILESO=C(N1CC/C(CC1)=C2C3=C(CCC4=CC=C[N+]([O-])=C4\2)C=C(Cl)C=C3)OCC
Biological Activity
DescriptionLoratadine n-oxide is a metabolite of the antihistamine Loratadine, acting as a competitive antagonist of peripheral histamine H1 receptors. This compound exhibits antihistaminic activity, making it useful in research focused on allergic responses and related pathways. Its role in understanding the pharmacokinetics and pharmacodynamics of antihistamines provides valuable insights for studies on allergy treatment and management.
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