Product Data Sheet
JNJ-10181457
Catalog No. A34120
JNJ-10181457 is a selective non-imidazole antagonist of the histamine H3 receptor, known to normalize acetylcholine neurotransmission. This compound also serves as a click chemistry reagent, featuring an alkyne group that enables it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions. Its properties make it valuable for insights into neurological signaling and the development of innovative chemical biology applications.
Chemical Information
| Catalog Num | A34120 |
|---|---|
| M. Wt | 312.45 |
| Formula | C20H28N2O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 544707-19-9 |
| Synonyms | |
| SMILES | C1(C#CCCN2CCCCC2)=CC(CN3CCOCC3)=CC=C1 |
Biological Activity
| Description | JNJ-10181457 is a selective non-imidazole antagonist of the histamine H3 receptor, known to normalize acetylcholine neurotransmission. This compound also serves as a click chemistry reagent, featuring an alkyne group that enables it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions. Its properties make it valuable for insights into neurological signaling and the development of innovative chemical biology applications. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
