Product Data Sheet
Antazoline phosphate
Catalog No. A34121
Antazoline phosphate is a potent H1 receptor antagonist that primarily modulates the central nervous system and exhibits significant antiarrhythmic properties. This compound effectively prevents histamine from binding to its receptor sites, leading to antiallergic effects and inhibition of physiological responses triggered by histamine. In addition, Antazoline phosphate has demonstrated a dose-dependent reduction of HBV DNA in both HepAD38 and Huh7 cells, with EC50 values of 2.910 μmol/L and 2.349 μmol/L, respectively. Its multifaceted biological activity makes Antazoline phosphate valuable for research applications in cardiovascular diseases and hepatitis B virus studies.
Chemical Information
| Catalog Num | A34121 |
|---|---|
| M. Wt | 363.35 |
| Formula | C17H22N3O4P |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 154-68-7 |
| Synonyms | Phenazoline phosphate |
| SMILES | O=P(O)(O)O.C1(CN(C2=CC=CC=C2)CC3=CC=CC=C3)=NCCN1 |
Biological Activity
| Description | Antazoline phosphate is a potent H1 receptor antagonist that primarily modulates the central nervous system and exhibits significant antiarrhythmic properties. This compound effectively prevents histamine from binding to its receptor sites, leading to antiallergic effects and inhibition of physiological responses triggered by histamine. In addition, Antazoline phosphate has demonstrated a dose-dependent reduction of HBV DNA in both HepAD38 and Huh7 cells, with EC50 values of 2.910 μmol/L and 2.349 μmol/L, respectively. Its multifaceted biological activity makes Antazoline phosphate valuable for research applications in cardiovascular diseases and hepatitis B virus studies. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
