Product Data Sheet

Impentamine dihydrobromide

Catalog No. A34149

main product photo
Impentamine dihydrobromide is a histamine H3 receptor antagonist known for its potent antihistamine activity. This compound demonstrates selective H3 antagonism, with a pA2 value of 8.4, indicating significant efficacy in guinea pig jejunum studies. Impentamine dihydrobromide binds specifically to the H3 receptor, making it valuable for research in neuropharmacology and related fields investigating histamine's role in neurotransmission and various physiological processes.
Chemical Information
Catalog NumA34149
M. Wt315.05
FormulaC8H17Br2N3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.149629-70-9
SynonymsVUF 4702 dihydrobromide
SMILESNCCCCCC1=CN=CN1.[H]Br.[H]Br
Biological Activity
DescriptionImpentamine dihydrobromide is a histamine H3 receptor antagonist known for its potent antihistamine activity. This compound demonstrates selective H3 antagonism, with a pA2 value of 8.4, indicating significant efficacy in guinea pig jejunum studies. Impentamine dihydrobromide binds specifically to the H3 receptor, making it valuable for research in neuropharmacology and related fields investigating histamine's role in neurotransmission and various physiological processes.
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