Product Data Sheet

FR-A-19

Catalog No. A34184

main product photo
FR-A-19 is a potent histamine H2-agonist, exhibiting IC50 values of 0.02 μM, 0.015 μM, and 0.008 μM against arpromidine, BUA-75, and FRA-19, respectively. This compound demonstrates significant anti-allergic properties and can be utilized in research aimed at understanding and mitigating allergic responses. Its mechanistic action on histamine receptors makes it a valuable tool for studies in allergy and inflammation.
Chemical Information
Catalog NumA34184
M. Wt548.93
FormulaC25H34Cl3F2N5
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.141099-46-9
Synonyms
SMILESN=C(NCCCC1=CN=CN1)N(CCCC2=CC=C(F)C=C2)CCCC3=CC=C(F)C=C3.[H]Cl.[H]Cl.[H]Cl
Biological Activity
DescriptionFR-A-19 is a potent histamine H2-agonist, exhibiting IC50 values of 0.02 μM, 0.015 μM, and 0.008 μM against arpromidine, BUA-75, and FRA-19, respectively. This compound demonstrates significant anti-allergic properties and can be utilized in research aimed at understanding and mitigating allergic responses. Its mechanistic action on histamine receptors makes it a valuable tool for studies in allergy and inflammation.
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