Product Data Sheet
JNJ-39220675
Catalog No. A34200
JNJ-39220675 is a selective antagonist of the histamine H3 receptor, specifically designed to penetrate the blood-brain barrier. This compound has demonstrated efficacy in modulating alcohol stimulation and reward, effectively reducing alcohol consumption and preference in alcohol-preferring rat models. Notably, JNJ-39220675 does not influence the ataxic effects of alcohol, the elimination rate of ethanol, or the dopamine release associated with alcohol exposure.
Chemical Information
| Catalog Num | A34200 |
|---|---|
| M. Wt | 369.43 |
| Formula | C21H24FN3O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 959740-39-7 |
| Synonyms | |
| SMILES | O=C(N1CCN(C2CCC2)CCC1)C3=CC=C(OC4=CC=C(F)C=C4)N=C3 |
Biological Activity
| Description | JNJ-39220675 is a selective antagonist of the histamine H3 receptor, specifically designed to penetrate the blood-brain barrier. This compound has demonstrated efficacy in modulating alcohol stimulation and reward, effectively reducing alcohol consumption and preference in alcohol-preferring rat models. Notably, JNJ-39220675 does not influence the ataxic effects of alcohol, the elimination rate of ethanol, or the dopamine release associated with alcohol exposure. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
