Product Data Sheet
GSK189254A hydrochloride
Catalog No. A34214
GSK189254A hydrochloride is a potent and selective antagonist of the histamine H3 receptor, exhibiting pKi values of 9.59-9.90 for human H3 and 8.51-9.17 for rat H3. This compound is useful in research applications focused on modulating neurotransmission and exploring the role of histamine in various physiological processes. Its selective antagonistic properties make it a valuable tool for studying the therapeutic potential in conditions such as neurodegeneration and cognitive disorders.
Chemical Information
| Catalog Num | A34214 |
|---|---|
| M. Wt | 387.90 |
| Formula | C21H26ClN3O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 945493-87-8 |
| Synonyms | GSK189254 |
| SMILES | O=C(NC)C(C=N1)=CC=C1OC2=CC(CC3)=C(C=C2)CCN3C4CCC4.Cl |
Biological Activity
| Description | GSK189254A hydrochloride is a potent and selective antagonist of the histamine H3 receptor, exhibiting pKi values of 9.59-9.90 for human H3 and 8.51-9.17 for rat H3. This compound is useful in research applications focused on modulating neurotransmission and exploring the role of histamine in various physiological processes. Its selective antagonistic properties make it a valuable tool for studying the therapeutic potential in conditions such as neurodegeneration and cognitive disorders. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
