Product Data Sheet

FAK-IN-14

Catalog No. A34252

main product photo
FAK-IN-14 is a potent inhibitor of focal adhesion kinase (FAK) with an IC50 value of 0.2438 nM. This compound has been shown to induce early apoptosis in U87-MG cells and effectively arrest the cell cycle at the G2/M phase. It is suitable for studies investigating the role of FAK in cancer biology and therapeutic applications targeting cell proliferation and survival.
Chemical Information
Catalog NumA34252
M. Wt502.43
FormulaC21H24BrN7OS
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2766666-22-0
Synonyms
SMILESCN(CC1)CCN1C(C=C2)=CC=C2NC3=NC=C(Br)C(NC4=C(C(NC)=O)SC=C4)=N3
Biological Activity
DescriptionFAK-IN-14 is a potent inhibitor of focal adhesion kinase (FAK) with an IC50 value of 0.2438 nM. This compound has been shown to induce early apoptosis in U87-MG cells and effectively arrest the cell cycle at the G2/M phase. It is suitable for studies investigating the role of FAK in cancer biology and therapeutic applications targeting cell proliferation and survival.
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