Product Data Sheet
VSLRGDTRG
Catalog No. A34288
VSLRGDTRG is a synthetic peptide derived from cadherin 17 (CDH17) that functions as a ligand for the α2β1 integrin. This peptide promotes the conformational activation of β1 integrin via the RGD motif, leading to enhanced cell adhesion and increased phosphorylation of FAK and ERK1/2. VSLRGDTRG is applicable in cancer research, specifically in studies involving tumors expressing CDH17, including colon and pancreatic cancers, where it may aid in understanding mechanisms of tumor proliferation and metastasis.
Chemical Information
| Catalog Num | A34288 |
|---|---|
| M. Wt | 960.05 |
| Formula | C38H69N15O14 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2027476-29-3 |
| Synonyms | |
| SMILES | [C@@H](NC([C@@H](NC([C@@H](NC([C@H](C(C)C)N)=O)CO)=O)CC(C)C)=O)(C(NCC(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(=N)N)C(NCC(O)=O)=O)=O)[C@@H](C)O)=O)CC(O)=O)=O)=O)CCCNC(=N)N |
Biological Activity
| Description | VSLRGDTRG is a synthetic peptide derived from cadherin 17 (CDH17) that functions as a ligand for the α2β1 integrin. This peptide promotes the conformational activation of β1 integrin via the RGD motif, leading to enhanced cell adhesion and increased phosphorylation of FAK and ERK1/2. VSLRGDTRG is applicable in cancer research, specifically in studies involving tumors expressing CDH17, including colon and pancreatic cancers, where it may aid in understanding mechanisms of tumor proliferation and metastasis. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
