Product Data Sheet

FAK-IN-10

Catalog No. A34294

main product photo
FAK-IN-10 is a potent inhibitor of focal adhesion kinase (FAK) with an IC50 of 76.3 µM. This compound demonstrates significant antitumor activity, particularly against the MCF-7 and A431 cell lines, exhibiting IC50 values of 4.23 µM and 0.78 µM, respectively. FAK-IN-10 is valuable for research focused on cancer therapeutics and the modulation of signaling pathways associated with tumor growth and metastasis.
Chemical Information
Catalog NumA34294
M. Wt376.23
FormulaC15H10BrN3O2S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.491839-65-7
Synonyms
SMILESO=C(CSC1=NN=C(C2=CC=NC=C2)O1)C3=CC=C(C=C3)Br
Biological Activity
DescriptionFAK-IN-10 is a potent inhibitor of focal adhesion kinase (FAK) with an IC50 of 76.3 µM. This compound demonstrates significant antitumor activity, particularly against the MCF-7 and A431 cell lines, exhibiting IC50 values of 4.23 µM and 0.78 µM, respectively. FAK-IN-10 is valuable for research focused on cancer therapeutics and the modulation of signaling pathways associated with tumor growth and metastasis.
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