Product Data Sheet
PF-07265807
Catalog No. A34306
PF-07265807 is a potent inhibitor of TAM receptors and the c-Met kinase, exhibiting IC50 values of 6.1 nM for AXL, 13.2 nM for MER, and 21.6 nM for TYRO3. This compound is primarily utilized in research focused on cancer biology, particularly in understanding tumor progression and metastasis. Its selective inhibition of specific tyrosine kinases offers valuable insights into therapeutic strategies targeting these pathways in oncology.
Chemical Information
| Catalog Num | A34306 |
|---|---|
| M. Wt | 591.57 |
| Formula | C29H27F2N7O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2412356-57-9 |
| Synonyms | |
| SMILES | OC[C@@H](C)NC1=NNC2=NC=CC(OC3=C(C=C(C=C3)NC(C(C(N4C5=CC=C(C=C5)F)=O)=CN(C(C)C)C4=O)=O)F)=C12 |
Biological Activity
| Description | PF-07265807 is a potent inhibitor of TAM receptors and the c-Met kinase, exhibiting IC50 values of 6.1 nM for AXL, 13.2 nM for MER, and 21.6 nM for TYRO3. This compound is primarily utilized in research focused on cancer biology, particularly in understanding tumor progression and metastasis. Its selective inhibition of specific tyrosine kinases offers valuable insights into therapeutic strategies targeting these pathways in oncology. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
