Product Data Sheet

c-Met-IN-19

Catalog No. A34343

main product photo
c-Met-IN-19 is a potent c-Met inhibitor with an IC50 of 1.99 nM. This compound exhibits significant cytotoxic effects on various cancer cell lines, including A549, HT-29, SGC-7901, and MDA-MB-231, demonstrating IC50 values of 0.25, 0.36, 0.98, and 0.76 μM, respectively. c-Met-IN-19 is valuable for research applications focused on cancer therapies targeting the c-Met pathway.
Chemical Information
Catalog NumA34343
M. Wt735.65
FormulaC34H37Cl2FN4O7S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.3098360-50-7
Synonyms
SMILESCOC1=CC2=C(N=CC=C2OC3=CC=C(NC(CCOC)=NS(=O)(CC4=C(Cl)C=CC=C4Cl)=O)C=C3F)C=C1OCCCN5CCOCC5
Biological Activity
Descriptionc-Met-IN-19 is a potent c-Met inhibitor with an IC50 of 1.99 nM. This compound exhibits significant cytotoxic effects on various cancer cell lines, including A549, HT-29, SGC-7901, and MDA-MB-231, demonstrating IC50 values of 0.25, 0.36, 0.98, and 0.76 μM, respectively. c-Met-IN-19 is valuable for research applications focused on cancer therapies targeting the c-Met pathway.
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