Product Data Sheet

BTK degrader-1

Catalog No. A34393

main product photo
BTK degrader-1 is a bifunctional degrader targeting Bruton’s tyrosine kinase (BTK) through its conjugation with CD79b. This compound facilitates the targeted degradation of BTK, leading to significant anti-tumor effects. It serves as a valuable tool for research applications focused on therapeutic strategies for hematological malignancies.
Chemical Information
Catalog NumA34393
M. Wt925.03
FormulaC52H54F2N8O6
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2377645-56-0
Synonyms
SMILESO=C(C1=CC=C(C(C)(C)O)C=C1F)NC2=CC(F)=CC(C3=C4C=C(C5=CC=C(CCN6CCC7(CC6)CCN(CC7)C(C8=CC=C(C(N9C(NC(CC9)=O)=O)=C8)OC)=O)C=C5)NC4=NC=N3)=C2C
Biological Activity
DescriptionBTK degrader-1 is a bifunctional degrader targeting Bruton’s tyrosine kinase (BTK) through its conjugation with CD79b. This compound facilitates the targeted degradation of BTK, leading to significant anti-tumor effects. It serves as a valuable tool for research applications focused on therapeutic strategies for hematological malignancies.
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SHIPPING AND STORAGE
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