Product Data Sheet
Acalabrutinib-d4
Catalog No. A34400
Acalabrutinib-d4 is a deuterated derivative of Acalabrutinib, an orally active and irreversible second-generation Bruton Tyrosine Kinase (BTK) inhibitor. This stable isotope labeled compound serves as a valuable tool for studying BTK inhibition in biological systems. Additionally, Acalabrutinib-d4 features an alkyne group, facilitating its use as a click chemistry reagent through copper-catalyzed azide-alkyne cycloaddition (CuAAc). Its applications extend to exploring therapeutic potential and pharmacokinetic properties in research settings.
Chemical Information
| Catalog Num | A34400 |
|---|---|
| M. Wt | 469.53 |
| Formula | C26H19D4N7O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2699608-18-7 |
| Synonyms | ACP-196-d4 |
| SMILES | O=C(NC1=NC([2H])=C([2H])C([2H])=C1[2H])C2=CC=C(C3=C4C(N)=NC=CN4C([C@H]5N(C(C#CC)=O)CCC5)=N3)C=C2 |
Biological Activity
| Description | Acalabrutinib-d4 is a deuterated derivative of Acalabrutinib, an orally active and irreversible second-generation Bruton Tyrosine Kinase (BTK) inhibitor. This stable isotope labeled compound serves as a valuable tool for studying BTK inhibition in biological systems. Additionally, Acalabrutinib-d4 features an alkyne group, facilitating its use as a click chemistry reagent through copper-catalyzed azide-alkyne cycloaddition (CuAAc). Its applications extend to exploring therapeutic potential and pharmacokinetic properties in research settings. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
