Product Data Sheet

BTK-IN-43

Catalog No. A34477

main product photo
BTK-IN-43 is a selective inhibitor of Bruton's tyrosine kinase (BTK) with an IC50 value of 21.6 nM. This compound is capable of oral administration and exhibits potent activity against BTK-mediated signaling pathways. It is primarily utilized in research applications focused on hematological malignancies and immune disorders driven by aberrant BTK activity.
Chemical Information
Catalog NumA34477
M. Wt514.48
FormulaC28H20F2N4O4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.3081685-04-0
Synonyms
SMILESCC(O)(C1=CC2=C(N3C(C4=CC=CC(N5C(NC6=C(C5=O)C=CC=C6F)=O)=C4F)=CC=C3C(N2)=O)C=C1)C
Biological Activity
DescriptionBTK-IN-43 is a selective inhibitor of Bruton's tyrosine kinase (BTK) with an IC50 value of 21.6 nM. This compound is capable of oral administration and exhibits potent activity against BTK-mediated signaling pathways. It is primarily utilized in research applications focused on hematological malignancies and immune disorders driven by aberrant BTK activity.
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