Product Data Sheet

AG-13958 (mono(hydrochloride))

Catalog No. A34804

main product photo
AG-13958 (mono(hydrochloride)) is a selective inhibitor of vascular endothelial growth factor receptor (VEGFR) tyrosine kinases. It demonstrates significant biological activity in inhibiting angiogenesis and has been investigated for its potential therapeutic applications in conditions such as choroidal neovascularization linked to age-related macular degeneration (AMD). This compound serves as a valuable tool in research focusing on the modulation of angiogenic pathways.
Chemical Information
Catalog NumA34804
M. Wt503.96
FormulaC26H23ClFN7O
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.319463-49-5
SynonymsAG-013958 monohydrochloride
SMILESO=C(C1=CC(C)=NN1C)NC(C=C2NC3=CC=C4C(/C=C/C5=CC=CC=N5)=NNC4=C3)=C(C=C2)F.Cl
Biological Activity
DescriptionAG-13958 (mono(hydrochloride)) is a selective inhibitor of vascular endothelial growth factor receptor (VEGFR) tyrosine kinases. It demonstrates significant biological activity in inhibiting angiogenesis and has been investigated for its potential therapeutic applications in conditions such as choroidal neovascularization linked to age-related macular degeneration (AMD). This compound serves as a valuable tool in research focusing on the modulation of angiogenic pathways.
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