Product Data Sheet
Emodic acid
Catalog No. A34844
Emodic acid is an anthraquinone compound that primarily targets and inhibits the activity of NF-κB, demonstrating significant anticancer properties. It effectively reduces the proliferation of cancer cells by inhibiting the phosphorylation of key proteins such as p38, ERK, and JNK. Additionally, Emodic acid suppresses the secretion of tumor-promoting cytokines IL-1β and IL-6, as well as the expression of vascular endothelial growth factor (VEGF) and matrix metalloproteinases (MMPs), thereby limiting the invasion and migration potential of cancer cells. This compound is valuable for research applications in cancer biology and therapeutic development.
Chemical Information
| Catalog Num | A34844 |
|---|---|
| M. Wt | 300.22 |
| Formula | C15H8O7 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 478-45-5 |
| Synonyms | NSC624610 |
| SMILES | OC1=CC(O)=CC(C(C2=C3C(O)=CC(C(O)=O)=C2)=O)=C1C3=O |
Biological Activity
| Description | Emodic acid is an anthraquinone compound that primarily targets and inhibits the activity of NF-κB, demonstrating significant anticancer properties. It effectively reduces the proliferation of cancer cells by inhibiting the phosphorylation of key proteins such as p38, ERK, and JNK. Additionally, Emodic acid suppresses the secretion of tumor-promoting cytokines IL-1β and IL-6, as well as the expression of vascular endothelial growth factor (VEGF) and matrix metalloproteinases (MMPs), thereby limiting the invasion and migration potential of cancer cells. This compound is valuable for research applications in cancer biology and therapeutic development. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
