Product Data Sheet

Vatalanib-d4

Catalog No. A34845

main product photo
Vatalanib-d4 is a deuterated form of Vatalanib, a potent inhibitor of the vascular endothelial growth factor receptor 2 (VEGFR2/KDR) with an IC50 of 37 nM. The stable isotope labeling of Vatalanib-d4 facilitates quantitative studies in pharmacokinetics, metabolism, and bioavailability. This compound is valuable for research in angiogenesis, cancer therapeutics, and related pathways.
Chemical Information
Catalog NumA34845
M. Wt350.84
FormulaC20H11D4ClN4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1246820-27-8
SynonymsPTK787-d4; ZK-222584-d4; CGP-79787-d4
SMILESClC(C([2H])=C1[2H])=C(C([2H])=C1NC2=NN=C(C3=CC=CC=C32)CC4=CC=NC=C4)[2H]
Biological Activity
DescriptionVatalanib-d4 is a deuterated form of Vatalanib, a potent inhibitor of the vascular endothelial growth factor receptor 2 (VEGFR2/KDR) with an IC50 of 37 nM. The stable isotope labeling of Vatalanib-d4 facilitates quantitative studies in pharmacokinetics, metabolism, and bioavailability. This compound is valuable for research in angiogenesis, cancer therapeutics, and related pathways.
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