Product Data Sheet

Lck degrader-1

Catalog No. A34951

main product photo
Lck degrader-1 is a molecular glue degrader that targets lymphocyte-specific protein tyrosine kinase (LCK) with a DC50 of 23.1 nM. This compound plays a significant role in the degradation of LCK, making it a valuable tool for studying T-cell acute lymphoblastic leukemia (T-ALL). Researchers can utilize Lck degrader-1 to explore the molecular mechanisms underlying T-ALL and investigate potential therapeutic strategies.
Chemical Information
Catalog NumA34951
M. Wt459.50
FormulaC25H25N5O4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.3095033-62-5
Synonyms
SMILESCCC1=C(NC2=C1C=CC=C2CN)C(NC3=CC4=C(C(N(C5CCC(NC5=O)=O)C4)=O)C=C3)=O
Biological Activity
DescriptionLck degrader-1 is a molecular glue degrader that targets lymphocyte-specific protein tyrosine kinase (LCK) with a DC50 of 23.1 nM. This compound plays a significant role in the degradation of LCK, making it a valuable tool for studying T-cell acute lymphoblastic leukemia (T-ALL). Researchers can utilize Lck degrader-1 to explore the molecular mechanisms underlying T-ALL and investigate potential therapeutic strategies.
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SHIPPING AND STORAGE
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