Product Data Sheet
Hibarimicin A
Catalog No. A34961
Hibarimicin A is a selective Src tyrosine kinase inhibitor derived from Microbispora rosea subsp. hibaria. It effectively inhibits Src activity while sparing protein kinases A and C, making it a valuable tool for studying cellular signaling pathways involving Src. In addition to its role as a kinase inhibitor, Hibarimicin A exhibits moderate antibacterial activity against Gram-positive bacteria, with a minimum inhibitory concentration (MIC) ranging from 0.8 to 12.56 μg/mL, broadening its potential applications in microbiology and pharmacology research.
Chemical Information
| Catalog Num | A34961 |
|---|---|
| M. Wt | 1725.78 |
| Formula | C85H112O37 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 208588-76-5 |
| Synonyms | |
| SMILES | CCCC12C3(C(C(C(C2O[C@@H]4O[C@@H]([C@H](CC4)O[C@H]5O[C@H](C(O)(CC5)C(C)=O)C)C)O)O[C@H]6C[C@H]([C@H]([C@@H](O6)C)O)O)([H])C(C7=C(O)C(C(C(OC)=C(C8=C(C(OC)=C9C(C(O)=C%10C(CC%11([H])C(C%10=O)(C(O)(C(C(C%11O[C@H]%12C[C@H]([C@H]([C@@H](O%12)C)O)O)O)O[C@@H]%13O[C@@H]([C@H](CC%13)O[C@@H]%14O[C@H]([C@@](O)(CC%14)C(C)=O)C)C)CCC)O)=C9)=C8O)OC)C%15=O)=O)=C%15C(O)=C7C3=O)([H])O1)O |
Biological Activity
| Description | Hibarimicin A is a selective Src tyrosine kinase inhibitor derived from Microbispora rosea subsp. hibaria. It effectively inhibits Src activity while sparing protein kinases A and C, making it a valuable tool for studying cellular signaling pathways involving Src. In addition to its role as a kinase inhibitor, Hibarimicin A exhibits moderate antibacterial activity against Gram-positive bacteria, with a minimum inhibitory concentration (MIC) ranging from 0.8 to 12.56 μg/mL, broadening its potential applications in microbiology and pharmacology research. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
