Product Data Sheet
TrkA-IN-4
Catalog No. A34979
TrkA-IN-4 is a potent allosteric inhibitor of TrkA, functioning as a proagent of TrkA-IN-3 with an IC50 value of 22.4 nM. This compound demonstrates significant antinociceptive effects, making it an important tool for research in pain modulation and neurobiology. Its orally active formulation enhances its utility in pharmacological studies exploring the role of TrkA in various pain-related pathways.
Chemical Information
| Catalog Num | A34979 |
|---|---|
| M. Wt | 538.47 |
| Formula | C27H21F3N4O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 3026111-74-7 |
| Synonyms | |
| SMILES | CC(OCOC(C1=CN=C(C(NC(C2=CC=C(C(C3=NN(C=C3)C)=C2)C(F)(F)F)=O)=C1)C4=CC=CC=C4)=O)=O |
Biological Activity
| Description | TrkA-IN-4 is a potent allosteric inhibitor of TrkA, functioning as a proagent of TrkA-IN-3 with an IC50 value of 22.4 nM. This compound demonstrates significant antinociceptive effects, making it an important tool for research in pain modulation and neurobiology. Its orally active formulation enhances its utility in pharmacological studies exploring the role of TrkA in various pain-related pathways. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
