Product Data Sheet
GZ-389988
Catalog No. A35005
GZ-389988 is a potent pan-TRK inhibitor that targets TRKA, TRKB, and TRKC with IC50 values of 0.3 nM, 0.1 nM, and 0.5 nM, respectively. It is valuable for the study of NTRK fusion-positive tumors, facilitating research into their biological mechanisms and potential therapeutic strategies. This compound supports the investigation of TRK-related pathways and their role in oncogenesis.
Chemical Information
| Catalog Num | A35005 |
|---|---|
| M. Wt | 470.52 |
| Formula | C26H26N6O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1788906-96-6 |
| Synonyms | |
| SMILES | NC1=NC2=CC(C3=CN(C)N=C3)=CN=C2N1CC4=CC=C(OCC5=CC=C(OC)C=C5)C(OC)=C4 |
Biological Activity
| Description | GZ-389988 is a potent pan-TRK inhibitor that targets TRKA, TRKB, and TRKC with IC50 values of 0.3 nM, 0.1 nM, and 0.5 nM, respectively. It is valuable for the study of NTRK fusion-positive tumors, facilitating research into their biological mechanisms and potential therapeutic strategies. This compound supports the investigation of TRK-related pathways and their role in oncogenesis. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
