Product Data Sheet

TrkA-IN-8

Catalog No. A35039

main product photo
TrkA-IN-8 is a potent TrkA inhibitor with a Kd value of 3.3 µM. This compound demonstrates concentration-dependent inhibition of cell proliferation in lung cancer cell lines, particularly in non-small cell lung cancer. TrkA-IN-8 is valuable for research applications aimed at understanding the role of TrkA signaling in oncogenesis and therapeutic resistance.
Chemical Information
Catalog NumA35039
M. Wt312.37
FormulaC20H16N4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.128889-33-8
Synonyms
SMILESNC1=CC2=C(C3=CC=CC=C3)N=C(C4=CC=C(N)C=C4)N=C2C=C1
Biological Activity
DescriptionTrkA-IN-8 is a potent TrkA inhibitor with a Kd value of 3.3 µM. This compound demonstrates concentration-dependent inhibition of cell proliferation in lung cancer cell lines, particularly in non-small cell lung cancer. TrkA-IN-8 is valuable for research applications aimed at understanding the role of TrkA signaling in oncogenesis and therapeutic resistance.
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.