Product Data Sheet
Atalaphyllidine
Catalog No. A35049
Atalaphyllidine is a selective inhibitor of DYRK1A kinase, demonstrating an IC50 of 2.2 μM. This natural product, derived from the stem bark of Glycosmis chlorosperma, plays a significant role in regulating protein phosphorylation, making it valuable in studies related to neurodegenerative diseases. Its specific mechanism of action positions Atalaphyllidine as a useful tool in understanding the pharmacological modulation of DYRK1A and its implications in various cellular processes.
Chemical Information
| Catalog Num | A35049 |
|---|---|
| M. Wt | 309.32 |
| Formula | C18H15NO4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 57959-88-3 |
| Synonyms | |
| SMILES | O=C1C2=C(NC3=C4C=CC(C)(C)OC4=CC(O)=C13)C(O)=CC=C2 |
Biological Activity
| Description | Atalaphyllidine is a selective inhibitor of DYRK1A kinase, demonstrating an IC50 of 2.2 μM. This natural product, derived from the stem bark of Glycosmis chlorosperma, plays a significant role in regulating protein phosphorylation, making it valuable in studies related to neurodegenerative diseases. Its specific mechanism of action positions Atalaphyllidine as a useful tool in understanding the pharmacological modulation of DYRK1A and its implications in various cellular processes. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
