Product Data Sheet
Leucettinib-92
Catalog No. A35062
Leucettinib-92 is a selective inhibitor of DYRK and CLK kinases, demonstrating IC50 values of 147 nM for CLK1, 39 nM for CLK2, 5.2 nM for CLK4, and 124 nM for DYRK1A, among others. This compound exhibits significant biological activity by modulating kinase signaling pathways, making it a valuable tool for research in oncology and neurodegenerative diseases. Its potency against key kinases provides potential insights into therapeutic targeting and intervention strategies in various cellular processes.
Chemical Information
| Catalog Num | A35062 |
|---|---|
| M. Wt | 378.49 |
| Formula | C21H22N4OS |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2732859-57-1 |
| Synonyms | |
| SMILES | O=C(N1)/C(N=C1NC2(C3)C[C@H]4C[C@@H]3C[C@@H](C2)C4)=C/C5=CC=C(N=CS6)C6=C5 |
Biological Activity
| Description | Leucettinib-92 is a selective inhibitor of DYRK and CLK kinases, demonstrating IC50 values of 147 nM for CLK1, 39 nM for CLK2, 5.2 nM for CLK4, and 124 nM for DYRK1A, among others. This compound exhibits significant biological activity by modulating kinase signaling pathways, making it a valuable tool for research in oncology and neurodegenerative diseases. Its potency against key kinases provides potential insights into therapeutic targeting and intervention strategies in various cellular processes. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
