Product Data Sheet
Protein kinase inhibitor 1
Catalog No. A35074
Protein Kinase Inhibitor 1 is a selective inhibitor of dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A), demonstrating an IC50 of 74 nM and a Kd of 9.5 nM. This compound is instrumental in the investigation of DYRK1A's role in various cellular processes, including neurodevelopment and cancer progression. It serves as a valuable tool for research applications focused on kinase signaling pathways and their implications in disease states.
Chemical Information
| Catalog Num | A35074 |
|---|---|
| M. Wt | 383.42 |
| Formula | C18H17N5O3S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1365986-44-2 |
| Synonyms | |
| SMILES | O=C(NC/1=O)SC1=C\C2=CNC(C(C3=CC=C(N4CCNCC4)N=C3)=C2)=O |
Biological Activity
| Description | Protein Kinase Inhibitor 1 is a selective inhibitor of dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A), demonstrating an IC50 of 74 nM and a Kd of 9.5 nM. This compound is instrumental in the investigation of DYRK1A's role in various cellular processes, including neurodevelopment and cancer progression. It serves as a valuable tool for research applications focused on kinase signaling pathways and their implications in disease states. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
