Product Data Sheet
Dyrk1A-IN-1
Catalog No. A35085
Dyrk1A-IN-1 is a selective inhibitor of Dyrk1A kinase activity, demonstrating an IC50 of 119 nM. This compound effectively inhibits the aggregation of tau and α-synuclein oligomers, making it a valuable tool for investigating neurodegenerative diseases. Its capacity to modulate kinase activity and prevent protein aggregation highlights its potential in studying pathways associated with tauopathies and synucleinopathies.
Chemical Information
| Catalog Num | A35085 |
|---|---|
| M. Wt | 432.49 |
| Formula | C23H20N4O3S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2858696-72-5 |
| Synonyms | |
| SMILES | O=C(NC1=NC2=C(C=C(O)C=C2)S1)NC3=CC=C(C(NCCC4=CC=CC=C4)=O)C=C3 |
Biological Activity
| Description | Dyrk1A-IN-1 is a selective inhibitor of Dyrk1A kinase activity, demonstrating an IC50 of 119 nM. This compound effectively inhibits the aggregation of tau and α-synuclein oligomers, making it a valuable tool for investigating neurodegenerative diseases. Its capacity to modulate kinase activity and prevent protein aggregation highlights its potential in studying pathways associated with tauopathies and synucleinopathies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
