Product Data Sheet
6-Methoxyflavone
Catalog No. A35314
6-Methoxyflavone is a methoxyflavone compound that primarily targets neuroinflammation pathways. It effectively suppresses neuroinflammation in microglia by inhibiting the TLR4/MyD88/p38 MAPK/NF-κB signaling cascade and activating HO-1/NQO-1 pathways. Additionally, 6-Methoxyflavone induces S-phase cell cycle arrest through the CCNA2/CDK2/p21CIP1 mechanism in HeLa cells. Its diverse biological activities make it valuable for research focused on cancer, inflammation, and neurological disorders.
Chemical Information
| Catalog Num | A35314 |
|---|---|
| M. Wt | 252.27 |
| Formula | C16H12O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 26964-24-9 |
| Synonyms | |
| SMILES | O=C1C=C(C2=CC=CC=C2)OC3=CC=C(OC)C=C13 |
Biological Activity
| Description | 6-Methoxyflavone is a methoxyflavone compound that primarily targets neuroinflammation pathways. It effectively suppresses neuroinflammation in microglia by inhibiting the TLR4/MyD88/p38 MAPK/NF-κB signaling cascade and activating HO-1/NQO-1 pathways. Additionally, 6-Methoxyflavone induces S-phase cell cycle arrest through the CCNA2/CDK2/p21CIP1 mechanism in HeLa cells. Its diverse biological activities make it valuable for research focused on cancer, inflammation, and neurological disorders. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
