Product Data Sheet
TLR8 agonist 2 hydrochloride
Catalog No. A35384
TLR8 Agonist 2 Hydrochloride is a highly potent and selective agonist for Toll-like receptor 8 (TLR8), exhibiting an EC50 value of 3 nM in human TLR8 assays. This compound demonstrates significantly lower activity against human TLR7, with an EC50 of 33.33 μM. Due to its specific activation of TLR8, this reagent is valuable for research applications involving immune response modulation and the study of pathogen recognition mechanisms.
Chemical Information
| Catalog Num | A35384 |
|---|---|
| M. Wt | |
| Formula | C16H22N8.xHCl |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2412937-65-4 |
| Synonyms | |
| SMILES | CCCC[C@@](CC1=NN=CN1)(C)NC2=NC(N)=NC3=C2C=CN=C3.[x].Cl |
Biological Activity
| Description | TLR8 Agonist 2 Hydrochloride is a highly potent and selective agonist for Toll-like receptor 8 (TLR8), exhibiting an EC50 value of 3 nM in human TLR8 assays. This compound demonstrates significantly lower activity against human TLR7, with an EC50 of 33.33 μM. Due to its specific activation of TLR8, this reagent is valuable for research applications involving immune response modulation and the study of pathogen recognition mechanisms. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
